When I saw what the crazy cats at Frontmotion were up to, I tripped out:
FrontMotion Firefox Community Edition is Firefox with the ability to lockdown settings through Active Directory using Administrative Templates. Similar to lockdown settings with mozilla.cfg on one computer, you can now use Administrative Templates to enforce settings across your organization. Two templates are provided to allow common and advanced settings.
They supply the templates and versions of Firefox ready to deploy in MSI format. Go here to check it out.
This nicely negates one of the big advantages many companies cite for staying with Internet Explorer. I'm interested in seeing how this pans out.